About this compound
MOTS-c is a 16-residue peptide encoded not in the nuclear genome but in mitochondrial DNA - specifically within the 12S rRNA region. It belongs to the small class of mitochondrial-derived peptides identified since 2015.
Studied in
- AMPK signalling
- Mitochondrial research
- Metabolic homeostasis
Compound identity
| Compound | MOTS-c |
|---|---|
| CAS number | 1627580-64-6 |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | 2,174.6 Da |
Specifications
- Purity method: HPLC
- Appearance: Lyophilized powder
- Solubility: Reconstitute per protocol; see Supplies for diluents.
- We don't publish a purity percentage here — that figure is only meaningful tied to the lot you actually receive, so it lives on the lot certificate.
Metabolic
THIRD GENOME
MOTS-c
Mitochondrial-derived peptide, studied in metabolic-homeostasis research.
What the research targets
Studied as a mitochondrial-derived peptide in AMPK signalling and metabolic-homeostasis models.
Supply formats
Single units ship from stock. Cases are back-ordered against the same single-unit price.
Skinni Stick™ is newly released — available alongside the vial on every compound.
Single unit
Sample quantity — one unit.
10 mgVial
PS-6963679-10-MG
On verified accountSkinni Stick™ 10 mgSkinni Stick™New
Single-compound Skinni Stick™. Supplied to verified accounts only.
PS-6963679-PEN-10-MG
On verified account
Case — back-order
Ten of one size, at 10× volume pricing.
Case · 10 × 10 mg
Back-order — 15% off the single-unit price.
PS-6963679-C10-10-MG
On verified accountCase · 10 × Skinni Stick™ 10 mgNew
Back-order — 15% off the single-unit price.
PS-6963679-C10-PEN-10-MG
On verified account
One-time verification of professional or institutional affiliation. No payment is taken on this site.
Research use only
This compound is supplied exclusively for laboratory research by qualified professionals and institutions. It is not a drug, dietary supplement, or cosmetic, and is not for human or veterinary use. We publish no dosing, administration, or human-use guidance of any kind, and nothing here should be read as a claim about an effect in people.
From the research library
Cited summaries of the published work behind MOTS-c — what was studied, in which model, and what was measured.
Metabolic
Amylin, a growth-hormone fragment, and two different evidence levels
Cagrilintide has a published phase 2 trial in humans. AOD-9604 has mouse work and a failed clinical programme. Both sit in the same catalog world.
Cellular
Mitochondrial peptides, cardiolipin and the NAD+ pool
The mitochondrial genome encodes signalling peptides of its own. Separately, a class of compounds targets the inner membrane directly.
Cellular
What a peptide actually is
Short chains of amino acids, the signalling vocabulary biology already speaks, and why they became one of the most active areas in drug discovery.
