Research library
The literature, read properly
Peptides are one of the most active areas in biology, and one of the worst-served by the writing about them. These articles do the unglamorous version: what investigators actually studied, in which system, and what they measured.
Every finding here names its model — cell line, rodent, or which human population in which trial. Every reference links out to the paper. Where the evidence is thin, inconsistent or negative, the article says so, because a catalog that only cites its good results is not worth reading.
- Articles
- 13
- Cited sources
- 30
- Dosing guides
- 0
Start here
Cellular
What a peptide actually is
Short chains of amino acids, the signalling vocabulary biology already speaks, and why they became one of the most active areas in drug discovery.
Supplies
How to read a certificate of analysis
What HPLC purity, mass-spectrometric identity, water content and endotoxin figures each tell you — and the several things a COA cannot tell you at all.
Regenerative
Matrikines: what the skin matrix says to itself
Collagen breakdown products act as signals, not just debris. The literature on GHK and copper coordination is the clearest worked example.
Endocrine
The growth-hormone axis, and four ways to poke it
GHRH analogues and ghrelin-receptor secretagogues act on different receptors with different consequences for pulsatility. The distinction is the whole subject.
By research world
The library is organised the same way the catalog is — by the question being asked rather than by the class of molecule.
- RegenerativeSkin, hair and tissue-repair research
- EndocrineGrowth-hormone axis and hormonal signalling research
- MetabolicEnergy, appetite and metabolic-signalling research
- NeurobiologyMood, memory and sleep-architecture research
- CellularMitochondrial, antioxidant and immune-signalling research
- SpecialtyPigmentation and other specialised research targets
- SuppliesReconstitution solvents and bench consumables
All articles
Supplies
Handling lyophilised peptides at the bench
Freeze-drying buys stability and introduces its own failure modes. Most degradation in practice happens before an experiment starts.
Cellular
Thymic peptides: an immunomodulator with a long paper trail
Thymosin alpha-1 has been studied since the 1970s, is licensed in a number of countries, and has a mechanistic account centred on Toll-like receptor signalling.
Endocrine
Upstream of GnRH: kisspeptin, and the oxytocin comparison
Kisspeptin sits above the classical reproductive axis and was identified through a human genetic disorder. Oxytocin is the opposite case — long known, recently complicated.
Specialty
The melanocortin receptors, and a cautionary case
Five receptors, one peptide family, and two compounds whose human records could hardly be more different. One has a phase 3 programme; the other has regulatory warnings.
Metabolic
Amylin, a growth-hormone fragment, and two different evidence levels
Cagrilintide has a published phase 2 trial in humans. AOD-9604 has mouse work and a failed clinical programme. Both sit in the same catalog world.
Neurobiology
Neuropeptides: ACTH fragments, a sleep factor, and VIP
Three research lines with very different provenance — Soviet-era clinical pharmacology, a 1977 isolation that never fully resolved, and a well-characterised receptor system.
Cellular
Mitochondrial peptides, cardiolipin and the NAD+ pool
The mitochondrial genome encodes signalling peptides of its own. Separately, a class of compounds targets the inner membrane directly.
Regenerative
PepT1, and a three-residue fragment of a larger hormone
KPV is the C-terminal tripeptide of alpha-MSH. The interesting part of its literature is how it gets into a cell.
Endocrine
The growth-hormone axis, and four ways to poke it
GHRH analogues and ghrelin-receptor secretagogues act on different receptors with different consequences for pulsatility. The distinction is the whole subject.
Regenerative
Tissue repair: actin, vessels and animal wound models
Two of the most requested research peptides sit on entirely different mechanistic evidence. Reading them side by side is instructive.
Regenerative
Matrikines: what the skin matrix says to itself
Collagen breakdown products act as signals, not just debris. The literature on GHK and copper coordination is the clearest worked example.
Supplies
How to read a certificate of analysis
What HPLC purity, mass-spectrometric identity, water content and endotoxin figures each tell you — and the several things a COA cannot tell you at all.
Cellular
What a peptide actually is
Short chains of amino acids, the signalling vocabulary biology already speaks, and why they became one of the most active areas in drug discovery.
How to read this library
Nothing here is about people. Every statement is a statement about a study — its system, its endpoint, its result. None of it describes what a compound would do in a person, and none of it is medical advice.
No dosing, anywhere. Not in an article, not on a compound page, not on request. Protocol design belongs to the investigator running the work.
Negative results are included. A compound whose clinical programme failed, or whose mechanism is unresolved after fifty years, is written up that way. See the metabolic article and the neuropeptide article.