A clear TB-500 research vial on a coloured plaster ledge, with botanicals beside it

About this compound

TB-500 is the synthetic acetylated form of the active region of Thymosin Beta-4, a 43-residue actin-sequestering peptide found across most mammalian tissue and one of the most abundant intracellular peptides characterised to date.

Studied in

Actin regulation
Cell migration
Tissue-repair models

Compound identity

Compound	TB-500
CAS number	77591-33-4
Molecular formula	C212H350N56O78S
Molecular weight	4,963.44 Da

Specifications

Purity method: HPLC
Appearance: Lyophilized powder
Solubility: Reconstitute per protocol; see Supplies for diluents.
We don't publish a purity percentage here — that figure is only meaningful tied to the lot you actually receive, so it lives on the lot certificate.

Regenerative

FILAMENT

TB-500

Thymosin Beta-4 fragment, studied in cell-migration research.

What the research targets

Studied in actin-regulation and cell-migration pathways relevant to tissue-repair research.

Supply formats

Single units ship from stock. Cases are back-ordered against the same single-unit price.

Stick is newly released — available alongside the vial on every compound.

Single unit

Sample quantity — one unit.

10 mgVial
PS-1698961-10-MG
On verified account
Skinni Stick™ 10 mgSkinni Stick™New
Single-compound Skinni Stick™. Supplied to verified accounts only.
PS-1698961-PEN-10-MG
On verified account

Case — back-order

Ten of one size, at 10× volume pricing.

Case · 10 × 10 mg
Back-order — 15% off the single-unit price.
PS-1698961-C10-10-MG
On verified account
Case · 10 × Skinni Stick™ 10 mgNew
Back-order — 15% off the single-unit price.
PS-1698961-C10-PEN-10-MG
On verified account

One-time verification of professional or institutional affiliation. No payment is taken on this site.

Research use only

This compound is supplied exclusively for laboratory research by qualified professionals and institutions. It is not a drug, dietary supplement, or cosmetic, and is not for human or veterinary use. We publish no dosing, administration, or human-use guidance of any kind, and nothing here should be read as a claim about an effect in people.

From the research library

Cited summaries of the published work behind TB-500 — what was studied, in which model, and what was measured.

All articles

Regenerative

Tissue repair: actin, vessels and animal wound models

Two of the most requested research peptides sit on entirely different mechanistic evidence. Reading them side by side is instructive.

August 11, 20269 min read